3063-71-6 CMP-Neu5Ac.2Na CMP-Sialic Acid, Monosodium Salt CAS 3063-71-6

CMP-sialic acid, monosodium salt is the active form of sialic acid. In mammalian cells, it has been shown to be required for the biosynthesis of complex carbohydrates containing sialic acid. Loss of CMP-sialic acid, production of monosodium salt, or feedback inhibitors of CMP-sialic acid led to gram-scale production of sialic acid by GLCNE (GNE, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase). This compound demonstrated the ability to neutralize various toxins by masking their binding sites. CMP-sialic acid, monosodium salt also provided protection against Neisseria gonorrhoeae through sialylation of Galβ1-4GlcNAc groups. It enhanced insulin reactivity, catalyzed by surface sialyltransferase, CMP-sialic acid, monosodium salt. This compound also demonstrated functions in blood protein half-life regulation, protection against glycoprotein lysis, and cell adhesion. CMP-sialic acid, monosodium salt is a substrate for sialyltransferase.

For Research Use Only. Not Intended for Therapeutic Use.