$
75.00+
THZ1 HCl THZ1 Hydrochloride CDK7 inhibitor 1604810-83-4
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THZ1 HCl THZ1 Hydrochloride CDK7 inhibitor 1604810-83-4
THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression.
| Cas No. | 1604810-83-4 | ||
Chemical Name | (E)-N-(3-((5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(4-(dimethylamino)but-2-enamido)benzamide hydrochloride | ||
Canonical SMILES | ClC(C=N1)=C(C2=CNC3=C2C=CC=C3)N=C1NC4=CC(NC(C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5)=O)=CC=C4.Cl | ||
Formula | C31H29Cl2N7O2 | M.Wt | 602.51 |
Solubility | ≥ 30.12mg/mL in DMSO | Storage | Store at -20°C |
For Laboratory R&D Use Only.
Brand
DiLab
Cat NO.
DL-80013A
Cas NO.
1604810-83-4
Formula
C31H29Cl2N7O2
MW
602.51
Purity
>98%
Price
$75.00