$
75.00+
Irbinitinib ARRY-380 ONT-380 Tucatinib 937263-43-9
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Irbinitinib ARRY-380 ONT-380 Tucatinib 937263-43-9
Biological Activity
Tucatinib, also known as Irbinitinib and ONT-380, is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (HER2). Irbinitinib selectively binds to and inhibits the phosphorylation of ErbB-2, which may prevent the activation of ErbB-2 signal transduction pathways, resulting in growth inhibition and death of ErbB-2-expressing tumor cells.
Chemical Information
| Molecular Weight | 480.52 |
Formula | C26H24N8O2 |
CAS Number | 937263-43-9 |
Solubility (25°C) | DMSO 40 mg/mL |
Storage | Powder -20°C 3 years ; 4°C 2 years |
In solvent -80°C 6 months ; -20°C 1 month |
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Brand
DiLab
Cat NO.
DL-16069
Cas NO.
937263-43-9
Formula
C26H24N8O2
MW
480.52
Purity
> 99%
Price
$75.00